Sodium nitroprusside dihydrate (CAS # 13755-38-9)

Meatotino tau vailaau:

Fuafua mole	C5H4FeN6Na2O3
Molar Mass	297.95
Malosi	1.72
Suavai Solubility	Solu i le vai. Ethanol laititi soluble.
Solubility	Solu i le vai (400 g/l) ile 20 °C, ma le ethanol (la'ititi soluble).
Fa'aaliga	tioata lanumumu loloto
Gravity Fa'apitoa	1.72
Lanu	Ruby mumu
Tapulaa o Fa'aaliga	ACGIH: TWA 1 mg/m3NIOSH: IDLH 25 mg/m3; TWA 1 mg/m3
Merck	14,8649
PH	5 (50g/l, H2O, 20 ℃)
Tulaga Teuteu	2-8°C
Ma'ale'ale	Hygroscopic
MDL	MFCD00149192
Meatotino Faaletino ma Vailaau	O le pauta tioata mumu-lanu enaena, e leai se manogi; Le tofo.
Fa'aoga	E faʻaaogaina e fai ma mea faʻapitoa mo le fuafuaina o aldehydes, acetone, sulfur dioxide, zinc, metals alkali, sulfides, ma isi.
Su'esu'ega in vitro	Sodium Nitroprusside o se vasodilator aoga. O le sodium nitroprusside e iai sona aafiaga vasodilatory lelei i arterioles ma venules. O le Sodium Nitroprusside e malepe i le taamilosaga e faʻasaʻo ai le nitric oxide (NO). NO e fa'agaoioia guanylate cyclase i maso lamolemole vascular ma fa'ateleina le gaosiga o le cGMP intracellular. E iu lava ina o'o atu i le malolo o maso lamolemole vascular, lea e fa'apalapala toto. O le sodium nitroprusside e faʻaitiitia ai le faʻateleina o maso lamolemole vascular.
Suʻesuʻe i vivo	Sodium nitroprusside (5 mg/kg) e pei o le nitric oxide foaʻi na faʻaitiitia ai le faʻaleagaina o le intestinal ischemia-reperfusion i isumu.

Auina imeli ia matou

Fa'amatalaga Oloa

Faailoga o oloa

Tulaga lamatia ma le Saogalemu

Tulaga lamatia	R25 – Oona pe a foloina R26/27/28 – O'ona tele pe a manava, fa'afeso'ota'i ma pa'u ma pe a folo.
Fa'amatalaga Saogalemu	S45 – I se fa'alavelave po'o ua e lagona le le lelei, saili vave fautuaga fa'afoma'i (fa'aali le igoa pe a mafai.) S36/37/39 – Fai ofu puipui talafeagai, totigilima ma mata/mata. S22 – Aua le manava pefu.
UN ID	UN 3288 6.1/PG 3
WGK Siamani	3
RTECS	LJ8925000
FLUKA BRAND F CODES	3
TSCA	Ioe
HS Code	28372000
Vasega o Tulaga Lamatia	6.1
Fa'aputu Vaega	III
Oona	LD50 tuugutu ile Lapiti: 99 mg/kg

13755-38-9 - Fa'asinomaga

Fa'asinomaga

Faaali atili

1. Tian, Ya-qin, et al. "Faatusatusaga o auala eseese e aveese mai ai ma le sili ona lelei o le microwave-assisted extrac...

13755-38-9 - Folasaga

Solu i le vai, solu teisi i le ava malosi. O lona vaifofo vai e le mautu ma e mafai ona faasolosolo malie ona pala ma liu lanu meamata.

13755-38-9 - Faʻamatalaga Faʻamatalaga

folasaga	sodium nitroprusside (fuafua mole: Na2[Fe(CN)5NO]· 2H2O, igoa vailaʻau: sodium nitroferricyanide dihydrate) o se vasodilator vave ma puʻupuʻu, lea o loʻo faʻaaogaina mo le faʻalavelave faʻafuaseʻi e pei o le faʻalavelave faʻafuaseʻi, encephalopathy hypertensive, toto maualuga leaga, toto maualuga paroxysmal i luma ma ina ua uma taotoga pheochromocytoma, ma isi, e mafai foi ona faaaoga mo le pulea. toto maualuga i le taimi ole taotoga fa'ama'i.
aafiaga	sodium nitroprusside o se vasodilator malosi vave, lea ei ai se aafiaga dilation tuusao i luga o maso lamolemole arterial ma venous, ma faaitiitia peripheral vascular tetee e ala i dilating ipu toto., Fausia aafiaga antihypertensive. E mafai foi e le fa'alolotoina o vasula ona fa'aitiitia le uta i luma ma pe a mae'a le fatu, fa'aleleia le fatu fatu, ma fa'aitiitia le fa'afefe o le toto pe a le tapunia le valve, ina ia mafai ai ona fa'amalolo fa'ailoga o le fatu.
fa'ailoga	1. e faʻaaogaina mo faʻalavelave faʻafuaseʻi o faʻalavelave faʻafuaseʻi, e pei o le hypertensive faʻalavelave, hypertensive encephalopathy, toto maualuga, paroxysmal toto maualuga i luma ma ina ua uma le taotoga pheochromocytoma, ma e mafai foi ona faʻaaogaina mo le pulea o le hypotension i le faʻamaʻi taotoga. 2. Mo le faaletonu o le fatu, e aofia ai le edema pulmonary mataʻutia. E faʻaaogaina foi mo le faʻaletonu o le fatu i le faʻalavelave faʻafuaseʻi o le myocardial poʻo le taimi e le tapunia ai le valve (mitral poʻo le aortic valve).
pharmacokinetics	e oʻo atu i le maualuga o le toto maualuga i le taimi lava e maeʻa ai le tui toto, ma o lona maualuga e faʻalagolago i le fua. O lenei oloa e metabolized e sela mumu toto i le cyanide, cyanide i le ate ua metabolized i thiocyanate, ma le metabolite e leai se gaoioiga vasodilating; e mafai foi ona auai le cyanide i le metabolism o le vaitamini B12. O lenei oloa e galue toetoe lava a maeʻa le faʻatonuga ma oʻo i le pito i luga o le gaioiga, ma faʻatumauina mo le 1 ~ 10 minute pe a uma le faʻamalo faʻamalo taofi. O le afa-ola o tagata mamaʻi e masani ona galue ile fatu e 7 aso (fuaina ile thiocyanate), faʻaumiumi pe a le lelei le gaioiga o le fatu poʻo le maualalo o le sodium toto, ma faʻamalo e le fatugaʻo.
O se faiga fa'akomepiuta mo tapenaga	sodium nitroprusside, e aofia ai laasaga nei: 1) Synthesizing copper nitroso ferrocyanide: faʻaopoopoina se aofaiga talafeagai o vai faʻamamaina e faʻamavae ai le potassium nitroso-ferricyanide i totonu o se tane tioata, faʻamafanafana i le 70-80 ℃ e faʻamavae atoa ai, ma faʻaopoopo lemu le kopa sulfate pentahydrate vaifofo dropwise, ina ua uma le tali e tausia mafanafana mo le 30 minute, centrifuge, le keke faamama centrifuged (copper nitroso ferricyanide) sa tuu i totonu o le tane tioata. 2) Synthetic sodium nitroprusside (sodium nitronitroferricyanide): Saunia saturated sodium bicarbonate aqueous solution e tusa ai ma le fua fafaga, ma faʻagasolo malie i le nitroso ferricyanide i le 30-60 degrees C. A maeʻa le tali, centrifuge, aoina filtrate ma lotion. 3) Fa'asa'o ma fa'ama'a'ai: O le filtrate ma le kulimi ua fa'aputuina o lo'o pamu i se tane fa'amama gaogao, ma fa'aopoopo lemu le acetic acid fa'ato'a fa'ato'a se'ia leai ni fa'apupulaina. Liliu le pamu mama ma vevela i luga o le 40-60 tikeri C, amata le faʻatonuga, taulai atu i se numera tele o tioata tioata, tapuni le vaʻa vaʻavaʻa, vacuum valve e sauniuni ai mo le tioata. 4) Faʻamago centrifugal: a maeʻa le faʻamalo, e aveese le supernatant, o tioata e faʻafefeteina ma faʻafefeteina, o le keke faamama e tuʻuina i totonu o se ipu uamea, ma o le oloa e maua i le faʻamagoina o le masini.
gaioiga fa'aletino	Sodium Nitroprusside o se vasodilator malosi e galue e ala i le tuʻuina faʻafuaseʻi ole NO ile toto.
Sini	Taua
Fa'aoga	Faʻaaogaina e fai ma mea faʻapitoa mo le fuafuaina o aldehydes, ketones, sulfides, zinc, sulfur dioxide, ma isi. Faʻaaogaina e fai ma mea faʻapitoa mo le fuafuaina o aldehydes, acetone, sulfur dioxide, zinc, Alkali metals, sulfides, ma isi. Vasodilators. Fa'amaoniga o aldehydes ma ketones, zinc, sulfur dioxide ma alkali metal sulfides. Su'esu'ega chromatic, su'ega urine.