(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER（CAS# 91229-91-3)

Folasaga

o le di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate o se fa'afefiloi o lona fua fa'a vaila'au o le C14H23NO6. O lo'o taua i lalo se fa'amatalaga o meatotino, fa'aoga, tapenaga ma fa'amatalaga saogalemu o le fa'aputuga:

natura:

-Fa'aaliga: di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate o se lanu e leai se lanu i le pa'epa'e tioata.

-Solubility: E solu i solu faʻaola pei ole ethanol, methanol ma dimethyl sulfoxide.

-I'uga liusuavai: E liusuavai le fa'afefiloi ile 104-105°C.

Fa'aaogā:

di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate o se mea faʻaaogaina amino acid e masani ona faʻaaogaina, e masani ona faʻaaogaina e avea o se reagent i le faʻaogaina o meaola. E mafai ona faʻaaogaina e faʻapipiʻi ai mea faʻaola olaola, e pei o vailaʻau ma mea polymer.

Metotia:

O le sauniuniga o le di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate e masani ona faia i laasaga nei:

1. Fa'amuta le pyroglutamic acid tert-butyl ester i le dimethyl sulfoxide mago.

2. Na fa'aopoopoina se aofa'iga talafeagai o le N,N'-dihydroxyethyl isopropanamide ma fa'amalieina le fa'afefiloi o tali i lalo ole 0°C.

3. Fa'aopoopo lemu le di-tert-butyl carbonate a'o fa'atumauina le vevela o le fa'afefiloi o tali i lalo ole 0°C.

4. A maeʻa le gaioiga, faʻapipiʻi le faʻafefiloi o tali i le vai e maua ai se paʻu malosi o le di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate.

5. O le oloa mulimuli na maua mai i laasaga o le tioata, faʻamama ma faʻamago.

Fa'amatalaga Saogalemu:

di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate e tatau ona faʻaaoga ma faʻatautaia e tusa ai ma faiga saogalemu e aloese ai mai le paʻu i le paʻu, mata ma le manava. E le gata i lea, e tatau ona teuina i se nofoaga matutu, malulu ma mamao ese mai afi ma oxidants. Mo fa'amatalaga fa'apitoa mo le saogalemu, va'ai ile Pepa o Fa'amatalaga mo le Saogalemu Kemisi (MSDS) po'o fa'amatalaga talafeagai e tu'uina mai e le fa'atau.