O loʻo faʻaauau pea ona faʻaleleia le faʻalapotopotoga o vailaʻau, faʻatasi ai ma mea faʻapitoa o loʻo faʻaalia mo o latou togafitiga faʻapitoa ma mea faʻapitoa faʻapitoa. O se tasi o vaega, 3-(trifluoromethyl)phenylacetic acid (CAS351-35-9), ua tosina atu i le Iunaite Setete ma Suitiselani. O lenei tusiga o loʻo suʻesuʻeina faiga o loʻo i ai nei, faʻamalosia maketi ma faʻamoemoega i le lumanaʻi o lenei tuufaatasiga i nei maketi taua e lua.
Vaaiga Aoao o Maketi
3-(Trifluoromethyl) phenylacetic acid o se vaʻavaʻa faʻaogaina i le tuʻufaʻatasia o vailaʻau eseese, aemaise lava i le atinaʻeina o vailaʻau faʻamaʻi ma analgesic. O lona vaega tulaga ese o le trifluoromethyl e faʻaleleia ai le lipophilicity ma le mautu o le metabolic o le mea e maua ai, ma avea ai ma filifiliga matagofie mo tagata atiaʻe vailaʻau. O le Iunaite Setete ma Suitiselani, e lauiloa mo a latou fale gaosi oloa, o loʻo taulamua i le atinaʻeina o le faʻalapotopotoga.
I totonu o le Iunaite Setete, o le maketi tau vailaʻau o loʻo faʻaalia i tulaga maualuga o mea fou ma suʻesuʻega faʻafaigaluega. O le iai o kamupani tetele o vailaau fa'asaina ma le fa'atonuga malosi a le FDA e fa'afaigofie ai le atina'eina ma le fa'atauina o vaila'au fou. Ole mana'oga mo le 3-(trifluoromethyl)phenylacetic acid e fa'amoemoe e fa'atupula'ia a'o taumafai kamupani e faia ni togafitiga sili atu ma le itiiti o a'afiaga.
Suiselani, i le isi itu, ua lauiloa ona o lona tulaga maualuga o le gaosiga o vailaʻau ma suʻesuʻega gafatia. O le atunu'u o lo'o i ai le tele o kamupani fa'afoma'i ta'uta'ua o lo'o fa'atupe tele i su'esu'ega ma atina'e. O le maketi a Suiselani e taulaʻi faʻapitoa i le atinaʻeina o vailaʻau saʻo ma togafitiga faʻatatau, lea e mafai ai e mea faʻapipiʻi pei ole 3-(trifluoromethyl)phenylacetic acid ona faia se sao taua.
Siosiomaga fa'atonutonu
O le Iunaite Setete ma Suiselani o loʻo i ai uma tulafono faʻatulafonoina mo le fale gaosi oloa. I totonu o le Iunaite Setete, e vaʻaia e le FDA le faʻagasologa o faʻatagaga mo vailaʻau fou ma faʻamautinoa latou te ausia tulaga saogalemu ma le aoga. E faʻapea foʻi, Suiselani o loʻo faʻatumauina tulaga faʻamaonia faʻamaonia fualaau i lalo o le Swiss Agency for Therapeutic Goods (Swissmedic). O nei pulega faʻatonutonu e taua tele i le faʻatulagaina o le maketi o le 3- (trifluoromethyl) phenylacetic acid aʻo latou aʻafia ai le saoasaoa o suʻesuʻega ma atinaʻe faʻapea foʻi ma le faʻalauiloaina o oloa fou.
Lu'itau Maketi
E ui lava i ana faʻamoemoega manuia, o le 3-(trifluoromethyl)phenylacetic acid maketi o loʻo feagai pea ma nisi o luitau. O se fa'alavelave tele o le tau maualuga o su'esu'ega ma atina'e, e ono taofia ai kamupani laiti mai le ulufale atu i le maketi. E le gata i lea, o le lavelave o le tu'ufa'atasia o lenei fa'aputuga ma le fa'amautinoaina o le tulaga lelei e tula'i mai ai lu'itau mo tagata gaosi oloa.
E le gata i lea, o le faʻalauteleina o fale talavai o loʻo taulaʻi atu i faiga gafataulimaina ma le siosiomaga e ono aʻafia ai auala gaosiga o le 3-(trifluoromethyl)phenylacetic acid. Kamupani o loʻo i lalo o le faʻamalosi e faʻaaogaina tekinolosi lanu meamata, lea e mafai ona oʻo atu ai i suiga i le sapalai o filifili ma le gaosiga o gaioiga.
fa'amoemoe
I le vaʻai atu i luma, o le 3-(trifluoromethyl) phenylacetic acid maketi e faʻamoemoe e tupu i le Iunaite Setete ma Suiselani. O le faʻateleina o faʻamaʻi faʻamaʻi ma le manaʻomia mo togafitiga fou o loʻo faʻaosoina ai le manaʻoga mo vailaʻau fou. A'o fa'aauauina su'esu'ega e fa'ailoa ai fa'aoga talafeagai mo lenei fa'aputuga, e mafai ona tatou va'aia le si'itia o lona fa'aogaina i le atina'eina o vaila'au.
E le gata i lea, o le galulue faatasi i le va o aʻoaʻoga faʻapitoa ma kamupani vailaʻau e faʻamoemoe e faʻaleleia le laufanua suʻesuʻe ma taʻitaʻia ai tusi talosaga ma faʻavae. O le taulaʻi atu i vailaʻau faʻapitoa ma togafitiga faʻapitoa o le a maua ai foi avanoa fou mo le 3-(trifluoromethyl)phenylacetic acid, ma avea ai ma tagata autu i le atinaʻeina o vailaʻau i le lumanaʻi.
I se aotelega, o le 3- (trifluoromethyl) phenylacetic acid pharmaceutical market i le Iunaite Setete ma Suiselani o loʻo i luga o se auala agai i luga, faʻamalosia e le faʻafouina, lagolago faʻatonutonu, ma le faʻatupulaia o manaʻoga mo fofo lelei. A'o fa'aauau pea le fa'atupuina o le alamanuia, e ono iai se sao taua o lenei fa'alapotopotoga i le fa'atulagaina o le lumana'i o vaila'au.
Taimi meli: Oke-30-2024