N-tert-Butoxacarbonyl-O-benzyl-L-threonine (CAS # 15260-10-3)

Folasaga
N-Boc-O-benzyl-L-threonine o se faʻalapotopotoga faʻapitoa. O lo'o ta'ua i lalo se folasaga i lona natura, fa'aoga, auala gaosi ma fa'amatalaga saogalemu:

Tulaga lelei:
N-Boc-O-benzyl-L-threonine o se tioata paʻepaʻe poʻo le paʻepaʻe paʻepaʻe, solu i solu masani masani e pei ole ethanol, dimethylformamide, chloroform, ma isi.

Fa'aaogā:
O le N-Boc-O-benzyl-L-threonine o se mea taua tele i le faʻaogaina o meaola ma e masani ona faʻaaogaina i le faʻaogaina o peptides ma proteins. E mafai ona faʻaaogaina e avea o se vaega puipuia i le faʻapipiʻiina o le vaʻavaʻa, faʻapipiʻi vai-vaega ma le ethanolamine-mediated synthesis e puipuia ai le tali atu o le threonine i le gaioiga o le tali, ina ia faʻaleleia ai le filifilia ma le maua o le tali.

Metotia:
O le sauniuniga o le N-Boc-O-benzyl-L-threonine e masani lava ona faia e ala ile faʻasologa o vailaʻau. Threonine ua acylated ma N-tert-butoxycarbonyl (Boc-O-benzyl) ma activators pei ole N,N-diisopropylethylamine (DIPEA) po o carbodiimide (DCC) ua faaopoopo. Ina ua uma le tali, na maua ai le N-Boc-O-benzyl-L-threonine.

Fa'amatalaga Saogalemu:
O le N-Boc-O-benzyl-L-threonine o loʻo i ai se faʻamatalaga maualuga o le saogalemu, ae i le avea ai o se vailaʻau faʻalaʻau, e tatau lava ona maitauina le puipuiga o le saogalemu: aloese mai le faʻafesoʻotaʻi ma le paʻu, mata ma le manava; Fai totigilima puipui, mata tioata, ma matapulepule pe a faagaoioi; Fa'agaoioi i totonu ose falesu'esu'e fa'alelei lelei; Aloese mai le fa'afeso'ota'i ma vaila'au fa'ama'i ma vaila'au pe a teu. Afai na pa'i fa'afuase'i pe manavaina, e tatau ona fufulu pe togafitia ile tausiga fa'afoma'i ile taimi.