N N'-Di-Boc-L-lysine hydroxysuccinimide ester（CAS# 30189-36-7)

Folasaga

N,N'-Di-Boc-L-lysine hydroxysuccinimide ester o se faʻapipiʻi faʻatasi ma se vailaʻau vailaʻau o le C18H30N4O7 ma le mamafa mole o le 414.45. O nisi nei o mea totino, fa'aoga, tapenaga ma fa'amatalaga saogalemu o le fa'apotopotoga:

natura:

-Fa'aaliga: Pa'epa'e malo

-Solubility: Solu i solu fa'aola pei ole dimethyl sulfoxide (DMSO) ma le Dimethyl Formamide (DMF)

-Melting Point: e uiga i 80-90 ℃

Fa'aaogā:

- N, N'-Di-Boc-L-lysine hydroxysuccinimide ester e masani ona faʻaaogaina e avea o se vaega puipuia i le peptide synthesis ma e mafai ona faʻaaogaina e faʻapipiʻi polypeptides ma polotini.

-E mafai ona faʻafeiloaʻi le succinimide (Boc) vaega puipuia i luga o le carboxyl group of amino acid, ona faʻafeiloaʻi lea o isi vaega e ala i le nucleophilic substitution reaction e faʻapipiʻi le polypeptide manaʻomia.

Metotia:

- N,N'-Di-Boc-L-lysine hydroxysuccinimide ester e mafai ona maua e ala i le taliina o le tuufaatasiga N,N'-di-tert-butoxycarbonyl-L-lysine (N,N'-Di-Boc-L-lysine) faʻatasi ai ma ester hydroxysuccinimide

-O le tali e masani lava ona faia i le vevela o le potu, o le taimi tali e tele itula i ni nai aso, ma o le oloa e faʻamamaina e ala i tioata e maua ai le mea e manaʻomia.

Fa'amatalaga Saogalemu:

- N, N'-Di-Boc-L-lysine o faʻamatalaga saogalemu o le hydroxysuccinimide ester e faʻatapulaʻaina, e masani ona manatu e maualalo le oona i totonu o se siosiomaga falesuesue.

-I le taimi o le tagofiaina ma le faʻagaioiga, e tatau ona faia ni puipuiga talafeagai, e pei o le ofuina o tioata puipui ma totigilima e faʻamautinoa ai le lelei o le ea.

-E tatau ona aloese mai le faʻafesoʻotaʻi o le vailaʻau ma paʻu, mata ma mucous membranes. Afai e iai se pa'i, fufulu vave i le tele o vai

-I le taimi o le teuina ma le taulimaina, aloese mai le faʻafesoʻotaʻi ma vailaʻau faʻamaʻi e aloese ai mai le afi poʻo le pa