Fmoc-L-Glutamic acid 1-tert-butyl ester（CAS# 84793-07-7)

Folasaga

Fluorene methoxycarbonyl-L-glutamate-1-tert-butyl ester, e taʻua foi o le Fmoc-L-glutamic acid-1-tert-butyl ester, o se mea faʻapipiʻi masani e masani ona faʻaaogaina i le peptide synthesis ma le solid-phase synthesis i le organic synthesis.

Tulaga lelei:

O le Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl o se mea mautu ma tioata paʻepaʻe i samasama. E maualalo le solubility i le vai ae lelei solubility i solution organic pei ole dimethyl sulfoxide po'o le methanol.

Fa'aaogā:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl o se vailaʻau amino puipuia e masani ona faʻaogaina i le peptide synthesis. E mafai ona faʻaaogaina e puipuia ai le vaega e ala i le tali atu, ina ia faʻaalia i le faʻasologa ma le faʻaopoopoga o filifili peptide. O lenei tuufaatasiga e sili ona talafeagai mo le faʻapipiʻiina o le faʻamalo, lea e fesoʻotaʻi ai filifili peptide i vailaʻau amino puipuia i lala resin.

Metotia:

O le sauniuniga o le fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl e masani lava ona ausia e ala i vailaʻau faʻasolosolo. O le fluorene methanol e muamua fa'apipi'iina i le fluorene carboxyl chloride e ala i vaila'au fa'ainisinia, ona fa'afo'i lea ma le L-glutamic acid e fai ai le fluorene methoxycarbonyl-L-glutamic acid, ma mulimuli ane tali atu i le tert-butanol e fausia ai le oloa mulimuli.

Fa'amatalaga Saogalemu:

Ole Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl e masani ona manatu e leai se o'ona manino i tagata i lalo ole tulaga masani fa'ata'ita'iga. E mana'omia ona mulimulita'i aiaiga talafeagai mo le saogalemu o falesu'esu'e i le taimi o le tagofiaina, e aofia ai le ofuina o totigilima ma matatioata puipui, ma fa'agaioi i tulaga fa'alelei lelei.