Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate（CAS# 211915-84-3 )

Folasaga

N-[[2-[[(4-cyanobenzenyl)amine]methyl]-1methyl-1H-5-benzimidazole]carbonyl]3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, faapuupuuina o le N-PCBMITPAAE. O lo'o ta'ua i lalo se folasaga i lona natura, fa'aoga, sauniuniga ma fa'amatalaga saogalemu:

Tulaga lelei:

Fa'aaliga: tioata lanu samasama po'o le lanu samasama.

Solubility: O le N-PCBMITPAAE e mafai ona solu i nisi vaifofo, e pei o le dimethyl sulfoxide ma le dichloromethane. E toetoe lava a le mafai ona solu i le vai.

Fa'aaogā:

O le N-PCBMITPAAE e masani ona faʻaaogaina i suʻesuʻega faʻapipiʻi i le matata o kemisi. O loʻo i ai se faʻalavelave mole faʻapipiʻi ma vaega malosi, ma e mafai ona faʻaaogaina e avea o se reagent, catalyst poʻo se sui faʻaopoopo i le faʻaogaina o meaola.

Metotia:

O le auala sauniuni o le N-PCBMITPAAE e lavelave ma e masani ona manaʻomia se tali e tele-laasaga. O se metotia masani o sauniuniga e aofia ai laasaga nei: faʻapipiʻiina o le 4-cyanoaniline ma le 1-methyl-1H-5-benzimidazole, ona faʻaalia lea i le carboatelic acid e fausia ai le N-[(4-cyanobenzene)methyl]-1-methyl-1H- 5-benzimidazole-2-carboxylate. O le isi, e tali atu i le 3-aminobenzoyl chloride e fausia ai le N-[(4-cyanobenzene)methyl]-1-methyl-1H-5-benzimidazole-2-carboxylic acid 3-aminobenzoyl ester. O le oloa mulimuli, N-PCBMITPAAE, e fa'atupuina e se tali fa'atasi ma le 2-pyridyl-β-alanine ethyl ester.

Fa'amatalaga Saogalemu:

O le fausaga o le N-PCBMITPAAE e sili atu ona faigata, ma e manaʻomia le faʻaeteete i le taimi o le faʻaogaina ma le faʻaogaina. E tatau ona mulimulita'i faiga su'esu'e talafeagai ma e tatau ona faia ni puipuiga talafeagai, e pei o le ofuina o totigilima puipui, talipupuni mata, ma mata. E tatau ona 'alo'ese mai fa'apogai fa'amumu ma fa'ama'i fa'ama'i malolosi, ma fa'atumauina tulaga lelei o le ea. Pe a teuina ma tagofia le vailaʻau, faʻamolemole pulea lelei e puipuia ai faʻalavelave.