Dodec-11-yn-1-ol（CAS# 18202-10-3)

Meatotino tau vailaau:

Fuafua mole	C12H22O
Molar Mass	182.3
Malosi	0.8530 (fa'atatau)
Lisi Lisi	18.8°C (fa'atatau)
Manu'a	285.73°C (fa'atatau fa'atatau)
pKa	15.20±0.10(Vavaloa)
Tulaga Teuteu	2-8°C
Fa'asino Upu	1.4535 (fa'atatau)

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Fa'amatalaga Oloa

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Dodec-11-yn-1-ol（CAS# 18202-10-3) Faamatalaga

sauniuniga

NaH(7.5g,60% suau'u ta'ape, 326mmol) na fa'aopoopoina fa'aputuga i le dodecyl -3-alkyne -1-alcohol (10.0g,54.95mmol;GF Smith) i totonu o se vaifofo 0 ℃ fa'aoso o le ethylenediamine (40mL). A maeʻa le 1h, ua siitia le vevela ile 70 ℃. A mae'a le isi 8h, fa'amalie le fa'afefiloiga tali i le 0°C, fa'amuta ma le fa'aeteete i le vai aisa-malulu (100mL), ma fa'apipi'i i le eter (3 × 60mL). O le su'ega eter fa'atasi na fufulu ile vai (100mL). Ole fufulu vai na toe ave'ese ile eter (3 × 60mL). O fa'aputuga fa'aola tu'ufa'atasi na fa'atumauina i lalo o le vacuum, ma o toega na tu'uina i le chromatography koluma e fa'aaoga ai le 10% EtOAc/hexane e maua ai le 11-dodecyne -1-alcohol (7.4g,74%) fa'aleagaina i le 3-5% o isi isomers fa'aitulagi ( regioisomer). TLC:30% EtOAc/hexane, Rf ≈ 0.4;1H NMR(300MHz,CDCl3)δ3.66(t,2H,J = 7.3Hz), 2.14-2.21(m,2H),1.93(t,J = 1.9Hz) ,1H),1.20-1.63(m,16H).

Muamua: N-(9-Fluorenylmethyloxycarbonyl)-N'-trityl-D-asparagine（CAS# 180570-71-2)

Sosoo ai: 4-Methoxyphenylhydrazine hydrochloride（CAS# 19501-58-7)

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