Carbobenzyloxy-beta-alanine（CAS# 2304-94-1)
| Fa'ailoga Mata'utia | Xn – Fa'aleagaina |
| Tulaga lamatia | R22 – E afaina pe a foloina R41 – Tulaga lamatia o le faaleagaina mata |
| Fa'amatalaga Saogalemu | S26 – Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga fa'afoma'i. S39 – Fai le puipuiga o mata/mata. |
| WGK Siamani | 2 |
| HS Code | 29242990 |
| Vasega o Tulaga Lamatia | FAAFITAU |
Folasaga
O se faʻalapotopotoga faʻapitoa lea na suia ai le vaega o le carboxyl (-COOH) i le alanine mole i totonu o le fausaga e le benzyloxycarbonyl (-Cbz) vaega.
Meatotino o le tuufaatasiga:
-Fa'aaliga: Pa'epa'e tioata pa'epa'e
-fuafua mole: C12H13NO4
-Molecular mamafa: 235.24g/mol
- Liu Liu: 156-160 ° C
O fa'aoga autu e fa'apea:
-I totonu o le fanua o le faʻaogaina o meaola, e mafai ona faʻaaogaina e avea o se vaeluaga mo le tuʻufaʻatasia o isi mea faʻapipiʻi lavelave.
-I le avea ai o se vaega puipuia mo vailaʻau polypeptide synthetic, e faʻaaogaina e puipuia ai toega alanine.
-Mo suʻesuʻega ma sauniuniga o isi meaola faʻalaʻau.
O le auala sauniuni e masani ona vaevaeina i laasaga nei:
1. O le tali a le benzyl chlorocarbamate ma le sodium carbonate e maua ai le benzyl N-CBZ-methylcarbamate (N-benzyloxycarbonylmethylaminoformate).
2. Tali le oloa na maua i le laasaga muamua i le sodium hydroxide solution e maua ai le N-CBZ-β-alanine.
E uiga i fa'amatalaga saogalemu:
-over e masani ona manatu e matua saogalemu, ae o loʻo manaʻomia pea faiga talafeagai.
- Aloese mai le fa'afeso'ota'i ma le pa'u, mata ma le gutu a'o fa'aoga.
- Fai totigilima puipui talafeagai, matatioata, ma ofutino falesuesue pe a fai su'ega.
- Aloese mai le manavaina o le pefu mai le fa'afefiloi.
-E tatau ona teuina le mea faʻapipiʻi i se nofoaga matutu, malulu, ma vavae ese mai mea e mu, vailaʻau faʻamaʻi ma isi mea.
E tatau ona maitauina o faʻamatalaga o loʻo tuʻuina atu iinei e mo naʻo le faʻamatalaga, ma o le tusi lesona faʻataʻitaʻi talafeagai ma le pepa faʻamaumauga o le saogalemu o vailaʻau e tatau ona faʻatalanoaina aʻo leʻi faʻaogaina le faʻaogaina, ma ia tusa ai ma tulafono faatonutonu mo le saogalemu o fale suʻesuʻe.
