Boc-D-aspartic acid 4-benzyl ester（CAS# 51186-58-4)

Folasaga

tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester (Boc-D-aspartic acid 4-benzyl ester) o se vailaʻau faʻaola. O lo'o taua i lalo se fa'amatalaga o meatotino, fa'aoga, tapenaga ma fa'amatalaga saogalemu o le fa'aputuga:

natura:

- Fa'aaliga: Pa'epa'e tioata malō

- Fuafuaga mole: C16H21NO6

-Molecular mamafa: 323.34g/mol

-mea liusuavai: 104-106 ℃

-Solubility: Solu i solu masani masani (e pei o le eter, methanol, ethanol)

Fa'aaogā:

-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester e masani ona faʻaaogaina e avea o se reagent i suʻesuʻega biochemical, faʻaaogaina e faʻapipiʻi pe suia isi faʻalapotopotoga faʻapitoa.

-E masani ona faʻaaogaina i le peptide synthesis e avea o se vaega puipuia mo le aspartic acid e puipuia ai le vaega galue i luga o le filifili o le amino acid ma faia se tali deprotection pe a manaʻomia.

Sauniuniga auala:

-E masani lava, Boc-D-aspartic acid 4-benzyl ester ua saunia e ala i le tali atu o le aspartic acid. Muamua, o le aspartic acid e tali atu i le acetyl chloride (AcCl) e maua ai le aspartic acid acetyl ester. O le acetyl protected aspartate acetyl ester ona fa'afoliga lea i le tert-butoxycarbonyl chloride (Boc-Cl) e maua ai le tert-butoxycarbonyl-D-aspartate 4-acetyl ester. Mulimuli ane, tert-butoxycarbonyl-D-aspartic acid 4-benzyl ester e mafai ona maua e ala i le esterification o le benzyl alcohol ma se faavae.

Fa'amatalaga Saogalemu:

- Boc-D-aspartic acid 4-benzyl ester e masani lava ona maualalo le oona, e tatau lava ona faia ni puipuiga talafeagai i le taimi o le taotoga, e pei o le ofuina o totigilima, mata tioata ma ofu suʻesuʻe.

- Aloese mai le fa'afeso'ota'i ma le pa'u ma le manava o le pefu.

- Teu i totonu o se nofoaga matutu, malulu, ese mai afi ma oxidizing agents.

-Pe a tagofia ma lafoai, faʻamolemole mulimuli i taʻiala talafeagai mo le faʻaogaina ma tulafono faatonutonu.