Boc-Asp-OtBu（CAS# 34582-32-6)

Folasaga

Boc-Asp-OtBu, e masani ona taʻua o Boc-Asp-OtBu, o se faʻalapotopotoga faʻapitoa. O lo'o ta'ua i lalo se fa'amatalaga i nisi o ona meatotino, fa'aoga, fa'atulagaina ma fa'amatalaga saogalemu:

natura:

- Fa'aaliga: Mea tioata lanu po'o mea pa'u.

- Fuafuaga mole: C≡H≡NO-7.

-Molecular mamafa: 393.47g/mol.

- Liu liusuavai: tusa o le 68-70°C.

-Solubility: Solu i totonu o nisi solvents organic, e pei o le dimethylformamide (DMF) ma le dichloromethane (DCM).

Fa'aaogā:

- Boc-Asp-OtBu o se vaega puipuia e masani ona faʻaaogaina, e masani ona faʻaaogaina i le tuʻufaʻatasia o peptides ma protein compounds. E mafai ona puipuia le carboxyl ma vaega amino o le glutamic acid (Asp) ma puipuia faʻalavelave faʻafuaseʻi ma faʻaleagaina.

- Boc-Asp-OtBu e mafai foi ona faʻaaogaina e fai ma tali faʻalavelave i le faʻaogaina o meaola, e pei o le peptide synthesis ma le vailaʻau faʻasaina.

Sauniuniga auala:

-E masani lava, o le Boc-Asp-OtBu e saunia e ala i le tali atu i le amino acid (L-glutamic acid) faʻatasi ma se vaega puipuia tert-butyl (Boc) ma se vaega puipuia tert-butoxycarbonyl (OtBu). O le tali e faia i lalo o tulaga talafeagai, mo se faʻataʻitaʻiga e ala i le faʻaopoopoina o se faʻamalosi e pei o le 1-(trimethylsilyl) -1H-pyrazol-3-one (TBTU) poʻo le N,N'-diisopropylmethylamide (DIPCDI) i totonu o se solvent organic.

Fa'amatalaga Saogalemu:

- Boc-Asp-OtBu ma le maualalo o le oona.

-Talu ai o se mea faʻaola, aloese mai le manavaina o le pefu pe faʻafesoʻotaʻi ma paʻu ma mata.

-Pe a faʻagaioi, e tatau ona e mulimulitaʻia faiga talafeagai mo le saogalemu o falesuesue, e pei o le ofuina o totigilima puipui ma le puipuiga o mata.

-Pe a teuina, e tatau ona teuina i totonu o se nofoaga malulu, matutu, ma mamao ese mai afi ma oxidizing agents.

O mea o lo'o i luga e mo na'o fa'amatalaga, fa'amolemole mulimuli i fa'amatalaga sa'o fa'ata'ita'iga kemikolo pe a fa'aaoga ma fa'atautaia le Boc-Asp-OtBu.