benzyl 3 6-dihydropyridine-1(2H)-carboxylate（CAS# 66207-23-6)

Folasaga

N-CBZ-1,2,3,6-tetrahydropyridine, e taʻua foi o le carbamate-4-hydroxybenzyl ester-1,2,3,6-tetrahydropyridine, o se faʻalapotopotoga faʻapitoa. O lo'o ta'ua i lalo se folasaga i ona meatotino, fa'aoga, auala gaosi ma fa'amatalaga saogalemu:

Tulaga lelei:

- N-Cbz-1,2,3,6-tetrahydropyridine o se paʻepaʻe paʻepaʻe.

- E mautu ile vevela ole potu ae pala ile vevela maualuga.

- E mafai ona solu i nisi vaifofo fa'aola pei ole dimethyl sulfoxide ma ethanol.

Fa'aaogā:

- N-Cbz-1,2,3,6-tetrahydropyridine e masani ona faʻaaogaina e avea o se vaega puipuia i le faʻaogaina o meaola e puipuia ai le vaega amino i le vaega amine. E puipuia le vaega amino mai tulaga le manaomia po o isi reagents i le tali.

Metotia:

- N-Cbz-1,2,3,6-tetrahydropyridine e mafai ona saunia e amination ma acylation. Tetrahydropyridine o loʻo faʻaalia i le carbamate e ala i se tali aminoation e gaosia ai le N-amino-1,2,3,6-tetrahydropyridine. Ona, N-amino-1,2,3,6-tetrahydropyridine e tali atu i le chloroformate e fausia ai le N-Cbz-1,2,3,6-tetrahydropyridine.

Fa'amatalaga Saogalemu:

- E fa'atapula'aina fa'amatalaga oona mo le N-Cbz-1,2,3,6-tetrahydropyridine, ae i se tulaga lautele, e ono i ai ni fa'aitaita'i ma le oona i tagata.

- 'Alo'ese le fa'afeso'ota'i sa'o ma le pa'u ma le manava o lona pefu a'o fa'aoga.

- O puipuiga talafeagai, e pei o totigilima ma mea faigaluega manava, e tatau ona faia i le taimi o le taulimaina ma le teuina.

- A fa'aoga ma teu, fa'amolemole mulimuli i ta'iala ma ta'iala mo le fa'aogaina saogalemu.