2-Bromo-5-(trifluoromethyl)pyridine（CAS# 50488-42-1)

Meatotino tau vailaau:

Fuafua mole	C6H3BrF3N
Molar Mass	225.99
Malosi	1.707±0.06 g/cm3(Va'ai)
Lisi Lisi	44-48 °C
Manu'a	78 °C
Mata'imu	78-81°C/30mm
Solubility	Solu i le methanol ma le ethanol.
Ausa Malo	0mmHg ile 25°C
Fa'aaliga	nila samasama susulu
pKa	-1?+-.0.10(Voloia)
Tulaga Teuteu	Taofi i se nofoaga pogisa, Faamaufa'ailoga i le matutu, Potu Tevela
Fa'asino Upu	1.572
MDL	MFCD00153086
Meatotino Faaletino ma Vailaau	tioata pa'epa'e
Fa'aoga	Fa'avae mo le palladium-catalyzed α-arylation o Refomatsky reagents

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Fa'amatalaga Oloa

Faailoga o oloa

Tulaga lamatia	R25 – Oona pe a foloina R36/37/38 – Fa'aitaita'i i mata, faiga manava ma le pa'u. R20/21/22 – E afaina pe a manava, pe a pa'u ma pe a folo.
Fa'amatalaga Saogalemu	S26 – Pe a pa'i i mata, fufulu vave i le tele o vai ma saili fautuaga fa'afoma'i. S36/37/39 – Fai ofu puipui talafeagai, totigilima ma mata/mata. S22 – Aua le manava pefu. S36 – Fai ofu puipui talafeagai.
UN ID	UN 2811 6.1/PG 3
WGK Siamani	3
HS Code	29333990
Vasega o Tulaga Lamatia	FAAFITAU
Fa'aputu Vaega	Ⅲ

Folasaga

2-Bromo-5-(trifluoromethyl)pyridine (faʻapitoa foi o le BTFP) o se faʻalapotopotoga faʻapitoa. O lo'o ta'ua i lalo se folasaga i lona natura, fa'aoga, auala sauniuni ma fa'amatalaga saogalemu:

Tulaga lelei:

- Fa'aaliga: Pa'epa'e malo

- Molecular mamafa: 206.00 g/mol

- Solubility: BTFP e faigofie ona solu i solu fa'aletino (fa'ata'ita'iga, ava malosi, ethers, ketones) ae itiiti solu i le vai.

Fa'aaogā:

- I le avea ai o se faʻasalalauga faʻapitoa: BTFP e faʻaaogaina lautele i le sauniuniga o mea faʻapipiʻi faʻasolosolo, e pei o pyridine compounds, aromatic compounds, etc.

- I le avea ai o se ligand: BTFP e mafai ona faʻaaogaina e avea o se ligand mo faʻalavelave uʻamea ma o loʻo aʻafia i faʻalavelave faʻalavelave faʻapitoa ma le saunia o mea aoga.

- I le avea o se reagent: BTFP e faia se sao taua i le tuʻufaʻatasiga o meaola, e pei o le faʻapipiʻiina o tali, faʻafeiloaʻi suiga, ma le faʻaitiitia o le tali.

Metotia:

2-Bromo-5-(trifluoromethyl) pyridine e mafai ona faʻapipiʻiina i laasaga nei:

1. Fa'amuta le 2-amino-5-(trifluoromethyl)pyridine i totonu o se solu fa'aletino talafeagai, e pei o le ava malosi po'o le ketone.

2. Fa'aopoopo mea fa'afefiloi (eg hydrogen bromide, methyl bromide).

3. Fa'atino le tali i le vevela sa'o ma tulaga fa'aoso.

4. Fa'amama le oloa ma fa'atino le fa'amamafa ma le fa'amamāina.

Fa'amatalaga Saogalemu:

- E mafai e le BTFP ona fa'amaua'i pe fa'a tioata i le vevela maualalo, fa'amolemole teu i le vevela o le potu ma aloese mai le fa'ama'a.

- Fai totigilima ma matatioata puipui talafeagai i le taimi o le taotoga e aloese ai mai le paʻi i le paʻu ma mata.

- Aloese mai le manavaina o lona pefu po'o le ausa, ona e ono i ai se aafiaga ita i le ala manava.

- Va'ai i le tusi lesona mo le saogalemu pe a fa'aaoga pe fa'aaogaina le BTFP, ma lafoa'i otaota ma vaifofo ma le talafeagai.

Muamua: Z-ASP-OBZL（CAS# 4779-31-1)